The name Gascoigne arrived in England after the Norman Conquest of 1066. The Gascoigne family lived in Yorkshire. Their name, however, is not a reference to this place, but to the family's place of residence prior their emigration to England, Gascony, a French province which was occupied by the English from 1152 until 1453. The surname was introduced to England following the Norman Conquest of 1066, as was the wine for which the area was known. Geoffery Chaucer's Old English poem Piers Plowman makes reference to "reed wyn of Gascoigne."
The medieval era saw many new names come to France. Gascoigne appeared at that time in the region called Gascogne. It was a name for someone who lived in the French province of Gascoigne or Gascony.